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Suppose You Are a Genetic Counsellor, and a Man and Woman

Question 56

Multiple Choice

Suppose you are a genetic counsellor, and a man and woman come to you with concerns that if they have a child together, it could have hemophilia. Also suppose that the woman has an X-linked recessive form of hemophilia, but the man does NOT. Which of the following is the best advice you could give them?


A) Each of their male offspring will have hemophilia, and each of their female offspring will have a 50% chance of having hemophilia.
B) Each of their male offspring will have a 50% chance of having hemophilia; and while their female offspring should not have hemophilia, they will each have a 50% chance of being carriers.
C) None of their offspring should have hemophilia, but each of their female offspring will be carriers for hemophilia.
D) Each of their male offspring will have hemophilia; and while their female offspring should not have hemophilia, they will all be carriers.

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