Which Description Is Consistent with Acute Lymphocytic Leukemia (ALL)

Multiple Choice

Which description is consistent with acute lymphocytic leukemia (ALL) ?

A) ALL is a progressive neoplasm defined by the presence of greater than 30% lymphoblasts in the bone marrow or blood.
B) Leukocytosis and a predominance of blast cells characterize the bone marrow and peripheral blood. As the immature blasts increase, they replace normal myelocytic cells, megakaryocytes, and erythrocytes.
C) B cells fail to mature into plasma cells that synthesize immunoglobulins.
D) The translocation of genetic material from genes 9 and 22 create an abnormal, fused gene identified as BCR-ABL.