Which of the Following Mitigation Strategies Would Be Most Likely

Multiple Choice

Which of the following mitigation strategies would be most likely to cause evolution of a drug-resistant strain of Plasmodium?

A) widespread, frequent spraying to kill mosquitoes
B) use of a cocktail of three drugs in patients suffering from malaria
C) widespread, frequent use of a single drug in patients suffering from malaria
D) widespread use of anti-mosquito bed nets