Which of the Following Is NOT True of Enzyme Behavior

Multiple Choice

Which of the following is NOT true of enzyme behavior?

A) Enzyme shape may change during catalysis.
B) The active site of an enzyme orients its substrate molecules, thereby promoting interaction of their reactive parts.
C) All enzymes have an active site where substrates are temporarily bound.
D) Each enzyme can catalyze only a specific reaction.
E) Enzyme activity is not affected by pH and temperature.