Which of the Following Statements Best Describes the Role of Calcium

Multiple Choice

Which of the following statements best describes the role of calcium in the release of a neurotransmitter substance from the presynaptic nerve terminal?

A) Calcium entry into the presynaptic terminal prevents the release of the neurotransmitter
B) Calcium entry into the presynaptic terminal is necessary for the release of the neurotransmitter
C) Calcium induces the opening of calcium-dependent sodium channels on the presynaptic terminal
D) Calcium entry into the presynaptic terminal results in the formation of cyclic adenosine monophosphate, which induces a conformational change in the presynaptic sodium channel that leads to the release of neurotransmitter