The Folding of Proteins Can Be Considered a Simple Conversion

Short Answer

The folding of proteins can be considered a simple conversion from the unfolded to the natively folded state. At about 27°C (or 300 K), the free-energy change of folding for a particular protein is measured to be -40 kJ/mole. If the enthalpy change (?H) of folding is -640 kJ/mole, what is the entropy change (?S) of folding for this protein? Write down your answer with the appropriate sign (+ or -) and in kJ/mole/K, e.g. -1000 kJ/mole/K.