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Neuromuscular Transmission Involves the Sequential Activation of Several Ion Channels

Question 35

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Neuromuscular transmission involves the sequential activation of several ion channels. Sort the following events to reflect the sequence leading to muscle contraction. Your answer would be a five-digit number composed of numbers 1 to 5 only, e.g. 12543.
(A) Opening of voltage-gated Na? channels in the muscle cell plasma membrane.
(B) Opening of Ca2+ release channels in the sarcoplasmic reticulum membrane.
(C) Opening of ionotropic acetylcholine receptors on the muscle cell plasma membrane.
(D) Opening of voltage-gated Ca2+channels in the T tubules.
(E) Opening of voltage-gated Ca2+channels in the motor neuron.

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