Solved

Consider a Transmembrane Protein with the Following Topology That Has

Question 39

Multiple Choice

Consider a transmembrane protein with the following topology that has an internal signal sequence (helix 1) . If you fuse a canonical ER signal sequence at the N-terminus of this protein, how would you expect the topology to change? The ER lumen is at the bottom in all drawings. For simplicity, assume that the effect of charged residues flanking the transmembrane helices is negligible in this case. Consider a transmembrane protein with the following topology that has an internal signal sequence (helix 1) . If you fuse a canonical ER signal sequence at the N-terminus of this protein, how would you expect the topology to change? The ER lumen is at the bottom in all drawings. For simplicity, assume that the effect of charged residues flanking the transmembrane helices is negligible in this case. A) B) C) D) E)


A) Consider a transmembrane protein with the following topology that has an internal signal sequence (helix 1) . If you fuse a canonical ER signal sequence at the N-terminus of this protein, how would you expect the topology to change? The ER lumen is at the bottom in all drawings. For simplicity, assume that the effect of charged residues flanking the transmembrane helices is negligible in this case. A) B) C) D) E)
B) Consider a transmembrane protein with the following topology that has an internal signal sequence (helix 1) . If you fuse a canonical ER signal sequence at the N-terminus of this protein, how would you expect the topology to change? The ER lumen is at the bottom in all drawings. For simplicity, assume that the effect of charged residues flanking the transmembrane helices is negligible in this case. A) B) C) D) E)
C) Consider a transmembrane protein with the following topology that has an internal signal sequence (helix 1) . If you fuse a canonical ER signal sequence at the N-terminus of this protein, how would you expect the topology to change? The ER lumen is at the bottom in all drawings. For simplicity, assume that the effect of charged residues flanking the transmembrane helices is negligible in this case. A) B) C) D) E)
D) Consider a transmembrane protein with the following topology that has an internal signal sequence (helix 1) . If you fuse a canonical ER signal sequence at the N-terminus of this protein, how would you expect the topology to change? The ER lumen is at the bottom in all drawings. For simplicity, assume that the effect of charged residues flanking the transmembrane helices is negligible in this case. A) B) C) D) E)
E) Consider a transmembrane protein with the following topology that has an internal signal sequence (helix 1) . If you fuse a canonical ER signal sequence at the N-terminus of this protein, how would you expect the topology to change? The ER lumen is at the bottom in all drawings. For simplicity, assume that the effect of charged residues flanking the transmembrane helices is negligible in this case. A) B) C) D) E)

Correct Answer:

verifed

Verified

Unlock this answer now
Get Access to more Verified Answers free of charge

Related Questions

Q34: According to the model for nuclear transport

Q35: Indicate true (T) and false (F) statements

Q36: The following diagram depicts the topology of

Q37: Indicate whether the C-terminus (C) or the

Q38: Sort the following events as they occur

Q40: Indicate true (T) and false (F) statements

Q41: Indicate whether each of the following transport

Q42: Consider a human cell such as a

Q43: Imagine a protein that has been engineered

Q44: Indicate true (T) and false (F) statements