If This Protein Is Unable to Hydrolyze Its Bound GTP

Multiple Choice

If this protein is unable to hydrolyze its bound GTP, invaginated clathrin-coated pits accumulate but fail to pinch off from the plasma membrane. In neurons, long vesicle necks collared by the protein are observed and presynaptic endocytosis is blocked. This protein …

A) contains a PI(4,5) P₂ binding domain and a GTPase domain.
B) recruits other proteins to the neck of the vesicle.
C) may change the membrane lipid composition by recruiting lipid-modifying enzymes.
D) may directly distort the membrane using the energy from GTP hydrolysis.
E) All of the above.