The Synthetic Toxin 2,4-Dinitrophenol Can Uncouple ATP Synthesis from Mitochondrial

Multiple Choice

The synthetic toxin 2,4-dinitrophenol can uncouple ATP synthesis from mitochondrial respiration by decreasing the permeability of the inner membrane to protons. What would be the effect of dinitrophenol treatment on the amount of ATP produced by mitochondria and on the rate of ATP transport across the inner membrane, respectively?

A) Positive; positive
B) Positive; negative
C) Negative; positive
D) Negative; negative