How Is Membrane Protrusion by Blebbing Different from That by Lamellipodia

Multiple Choice

How is membrane protrusion by blebbing different from that by lamellipodia?

A) Blebbing usually occurs on a rigid substratum such as glass, whereas lamellipodia form on pliable substrata.
B) Blebbing is mostly observed in vitro, whereas lamellipodia are observed both in vitro and in vivo.
C) Blebbing does not involve myosin II activity, but formation of lamellipodia does.
D) Blebbing requires loss of membrane interaction with actin filaments, whereas lamellipodia require a close interaction between the two.
E) All of the above.