Indicate Whether Each of the Following Mutations Would Likely Promote

Short Answer

Indicate whether each of the following mutations would likely promote (P) or inhibit (I) apoptosis in cells harboring the mutation(s). Your answer would be a four-letter string composed of letters P and I only, e.g. PPPI.
( ) Mutations in the pro-apoptotic effector Bcl2 family proteins Bax and Bak that prevent their association with the outer mitochondrial membrane.
( ) A mutation in the BIR domain of the IAP protein DIAP1 that prevents binding to either caspases or anti-IAP proteins.
( ) A mutation in the anti-IAP protein Reaper that prevents its binding to the IAP proteins.
( ) A mutation in the CARD domain of caspase-9 that prevents its binding to Apaf1.