I Find That Briefly Washing Cells in a Buffered Solution

Multiple Choice

I find that briefly washing cells in a buffered solution at pH 11 is effective for isolating a cell membrane-associated hormone receptor. (A standard growth solution for the cells is pH 7.) Which of following best fits this description?

A) This is an integral membrane protein that completely traverses the cell membrane.
B) This is an integral membrane protein that only penetrates one leaf of the cell membrane.
C) This is a peripheral membrane protein that probably interacts with membrane phospholipids using aspartate-mediated salt bridges.
D) This is a peripheral membrane protein that probably interacts with membrane phospholipids using lysine-mediated salt bridges.