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The Mechanism for All Template-Directed Synthesis of Any Type of Nucleic

Question 48

Multiple Choice

The mechanism for all template-directed synthesis of any type of nucleic acid involves the following:


A) Nucleophilic attack of a 3' hydroxyl toward a nucleoside triphosphate, releasing PPi.
B) Nucleophilic attack of a 5' hydroxyl toward a nucleoside triphosphate, releasing PPi.
C) Nucleophilic attack of a 3' hydroxyl toward a nucleoside triphosphate, releasing Pi.
D) Nucleophilic attack of a 5' hydroxyl toward a nucleoside triphosphate, releasing Pi.
E) More than one of these would work, since the mechanism is not universal.

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