Arrange the Events in the Pathway Activated by G-Protein-Coupled Receptors

Multiple Choice

Arrange the events in the pathway activated by G-protein-coupled receptors (GPCRs) in the correct order.
1.  Activation of effector
2.  Activation of protein kinases
3.  Receptor binds first messenger
4.  Production of second messenger
5.  Activation of G protein

A) 1→3→5→2→4
B) 2→3→5→4→1
C) 3→1→5→4→2
D) 3→5→1→4→2
E) 3→5→2→4→1