In His Experiments, Anfinsen Treated a Protein with a Chemical

Multiple Choice

In his experiments, Anfinsen treated a protein with a chemical that broke disulfide bonds and then removed the chemical to see how this would affect the function of the molecule. What did he conclude from these experiments?

A) The information for determining the three-dimensional shape of ribonuclease lies in its amino acid sequence.
B) The disulfide bonds are essential for quaternary, but not tertiary, protein structure.
C) Protein conformation is maintained when disulfide bonds are disrupted.
D) Altering the three-dimensional shape of the protein is irreversible.
E) Disulfide bonds are unnecessary for proper protein function.