In the United States, Sickle Cell Disease Is Seen Most

Multiple Choice

In the United States, sickle cell disease is seen most often in African Americans. Why is this?

A) African Americans are more likely to have had malaria.
B) African Americans are more prone to genetic diseases in general.
C) African Americans are more likely to be descendants of people who lived where malaria was prevalent, so the sickle cell mutation gave them an advantage and was passed on more frequently.
D) African Americans are more likely to be descendants of people who lived in an environment that caused the sickle cell mutation, giving them an advantage that was passed on more frequently.
E) African Americans are more likely to be descendants of people who were more attractive to mosquitoes, so the sickle cell mutation gave them an advantage.