With Respect to the Structure and Function of NAChRs, Cysteine

Multiple Choice

With respect to the structure and function of nAChRs, cysteine scanning

A) provided binding sites for tritiated chlorpromazine in the M2 helix.
B) refers to scanning for radioactivity of tritiated chlorpromazine after it reacts with cysteines in the M2 helix.
C) provided novel binding sites for QX222 in the open channel compared to existing QX222 biding sites in the native receptor.
D) revealed that amino acids at 2′, 3′, 6′, 8′, 9′, 10′, 13′, and 16′ lined the pore-forming side of the M2 helix.
E) revealed that amino acids at 2′, 6′, and 9′ lined the pore-forming side of the M2 helix.