Imagine You Want to Study Promoter X, Which Controls Many

Essay

Imagine you want to study Promoter X, which controls many of the genes in B cells that you believe are important for controlling viral infections.You want to generate a transgenic mouse line with a mutation in this promoter that makes it expressed at low levels.Unfortunately, after all of your work, you learn that your mutation is "embryonic lethal." Describe the strategies/techniques that could be used to circumvent this problem.