T Cells Are Frequently at Fault for Causing Damage in Autoimmune

Multiple Choice

T cells are frequently at fault for causing damage in autoimmune disorders and in transplant rejection.As an immunologist, your dream is to discover a method for decreasing T-cell response to self-antigens.Which of the following would be the BEST target for your research?

A) Activated B cells because they make T-cell receptor molecules
B) Antibody mediated apoptosis of dendritic cells
C) CTLA-4 antagonists that block the action of CTLA-4
D) Ligands that block the binding of one costimulatory molecule
E) Radiation therapy directed at all T cells