Bernard-Soulier Syndrome Is a Bleeding Disorder Caused by a Defect

Multiple Choice

Bernard-Soulier syndrome is a bleeding disorder caused by a defect of glycoprotein Ib (GpIb) on platelets. Platelets lacking GpIb cannot adhere to the wall of the damaged blood vessels, because GpIb is the receptor for which essential coagulation protein?

A) Hageman factor (factor XII)
B) Von Willebrand factor
C) Fibrinogen
D) Factor VIII
E) Thrombin