All of the Following Protein-Protein Interactions Are Involved in Activation

Multiple Choice

All of the following protein-protein interactions are involved in activation of naive helper T cells by antigen-presenting cells (APCs) EXCEPT:

A) Binding of peptide-MHC complexes on the APC to the TCR on the T cell
B) Binding of CD4 on the T cell to nonpolymorphic regions of class II MHC molecules on the APC
C) Binding of integrins on the T cell with adhesion ligands on the APC
D) Binding of B7-2 on the APC with CD28 on the T cell
E) Binding of CD40L on the T cell with CD40 on the APC