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All of the Following Are Early T Cell Events That

Question 9

Multiple Choice

All of the following are early T cell events that occur after antigen recognition by the TCR EXCEPT:


A) Formation of the immunologic synapse
B) Recruitment of signaling molecules,such as LAT,to glycolipid-enriched domains known as lipid rafts
C) Enhanced adhesion between T cells and antigen-presenting cells (APCs) via T cell integrin LFA-1 and its ligand on the APC,ICAM-1,at the central zone of the immunologic synapse
D) Clustering of the TCR and coreceptors leading to phosphorylation of ITAMs on CD3 by Lck
E) Binding of CD28 with costimulators on APCs in the cSMAC,resulting in signal transduction activation

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