Could Cancer Cells Be Selectively Targeted by Using Antibodies Recognizing

Multiple Choice

Could cancer cells be selectively targeted by using antibodies recognizing a tumor-specific protein marker? Researchers grafted human cancerous cells onto 20 healthy adult mice and then randomly assigned 10 of these mice to be treated with tumor-specific antibodies. They found that only 1 of the 10 mice treated with antibodies developed metastases (i.e., new cancer growth) , whereas all 10 of the 10 mice in the control group developed metastases. We want to compare the proportions of mice developing metastases under the two conditions. Which of the following statements is correct regarding this hypothesis test?

A) The test is not appropriate because the respective counts of successes and failures are not large enough.
B) The test is not appropriate because the experiment is not double-blind.
C) The test is appropriate because a total of 20 mice is large enough for any inference.
D) The test is appropriate because the study was randomized.