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Single-Stranded DNA and Unreplicated DNA Are Recognized by ATR, Which

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Single-stranded DNA and unreplicated DNA are recognized by ATR, which leads to G2 arrest. What would likely occur with a single-stranded DNA break in a cell with a mutation that prevented phosphorylation of Chk1? What if the mutation prevented phosphorylation of Chk2?

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Cells with a Chk1 mutation would not arr...

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