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How Does Nucleotide-Excision Repair Differ from Base-Excision Repair

Question 86

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How does nucleotide-excision repair differ from base-excision repair?


A) Base-excision repair recognizes and removes single damaged bases, whereas nucleotide-excision repair is more general, recognizing many different kinds of lesions that distort the DNA molecule.
B) Nucleotide-excision repair reverses the chemical reaction that caused the lesion, whereas base-excision repair removes the damaged bases and replaces them with normal ones.
C) Only the base is removed in base-excision repair, whereas the entire nucleotide is removed in nucleotide-excision repair.
D) Base-excision repair requires no protein components and can occur by simple absorption of UV light, whereas nucleotide-excision repair requires several enzymes.

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