Multiple Choice
In RNAi screens, siRNAs are incubated with cells in culture to assess functional consequences of the targeted gene. Which statement regarding siRNA and its action is true?
A) The siRNA is homologous to and binds intronic gene sequences, preventing appropriate RNA splicing.
B) The siRNA is homologous to and binds promoter sequences in the gene, preventing expression of the gene.
C) The siRNA is homologous to and binds exonic gene sequences, giving rise to a truncated nonfunctional protein.
D) The siRNA is homologous to and binds the mRNA, leading to degradation of the mRNA.
Correct Answer:
Verified
Correct Answer:
Verified
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