Which of the Following Is a Most Likely to Be

Multiple Choice

Which of the following is a most likely to be a drawback of a 2 x 3 x 4 x 5 factorial design?

A) The four-way interaction effect will be challenging to interpret.
B) Researchers will not be able to fully manipulate all the independent variables.
C) While the main effects might be significant, it is unlikely for any interaction to be significant.
D) Higher-level factorial designs have less generalizability than simpler experimental designs.