Which of the Following Is Not a Difference Between the Concerted

Multiple Choice

Which of the following is not a difference between the concerted model and the sequential model of allosteric enzymes?

A) The sequential model allows for different subunits to be in different conformations while the concerted model does not
B) Negative cooperativity can be explained by the sequential model but not by the concerted model
C) Positive cooperativity can be explained by the sequential model but not by the concerted model
D) The sequential model is explained better by considering the induced-fit model of substrate binding, whereas the concerted model focuses on perturbing the equilibrium between the T and R forms.