The Figure Below Illustrates Two Levels of DNA Packing in a Eukaryotic

Multiple Choice

The figure below illustrates two levels of DNA packing in a eukaryotic cell. Conformation B is an enlargement of the area in Conformation A, indicated by the start of the arrow. In which conformation is transcription most likely to occur?

A) Conformation A, because the tight coiling brings regulatory DNA sequences closer together.
B) Conformation A, because tight coiling only occurs during cell division, which is when transcription occurs.
C) Conformation B, because RNA polymerase can only access regulatory DNA when chromosomes are not condensed.
D) Conformation B, because in this conformation, the DNA is completely separated from histones that bind to regulatory DNA sequences preventing transcription.