Jacob and Monod Were Intellectually Primed to Draw the Conclusions

Multiple Choice

Jacob and Monod were intellectually primed to draw the conclusions they did concerning regulation of the lac operon. In part, this was due to their fascination with mechanisms of enzyme regulation. They knew that the activity of some enzymes is regulated when their reaction product binds to the enzyme, changing its shape and, therefore, its activity. This knowledge allowed them to easily make the intellectual leap to propose ________.

A) the existence of the CAP binding site
B) allosteric regulation of the repressor
C) positive regulation of the lac operon
D) the existence of the operator
E) co-transcribed and co-regulated genes of bacterial operons