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RNA Silencing Is Initiated by Double-Stranded RNA Molecules That Are

Question 4

Multiple Choice

RNA silencing is initiated by double-stranded RNA molecules that are cleaved and processed. The resulting siRNAs or miRNAs combine with proteins to form complexes that bind to complementary sequences in mRNA or DNA. The siRNAs and miRNAs affect gene expression by cleaving mRNA, inhibiting translation, altering chromatin structure, or triggering RNA degradation.
-In RNA silencing, siRNAs and miRNAs usually bind to which part of the mRNA molecules that they control?


A) 5' UTR
B) Segment that encodes amino acids
C) 3' poly(A) tail
D) 3' UTR

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