A Patient with a Cough of Several Weeks' Duration but No

Multiple Choice

A patient with a cough of several weeks' duration but no fever has radiological signs of a coin lesion. The needle biopsy shows large, broad-based budding yeasts with a very thick cell wall. Most of the yeasts are extracellular. What is the most likely diagnosis?

A) Aspergillosis
B) Blastomycosis
C) Coccidioidomycosis
D) Histoplasmosis
E) Cancer