Which of the Following Is NOT a Characteristic of Metal

Multiple Choice

Which of the following is NOT a characteristic of metal ion catalysis?

A) increased acidity of a nucleophile with an ionizable proton
B) metal ion requirement to maintain the stable,native state of the enzyme
C) strongly metal binding,perhaps not only during the catalytic cycle
D) electrophilic catalysis,stabilizing the increased electron density or negative charge that can develop during a reaction