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The Neurotrophic Hypothesis of Depression Is Supported by All of the Following

Question 22

Multiple Choice

The neurotrophic hypothesis of depression is supported by all of the following except


A) chronic stress decreases hippocampal brain-derived neurotrophic factor (BDNF) .
B) acute antidepressant treatment protects neurons by increasing BDNF.
C) chronic antidepressant treatment increases BDNF in both humans and animals.
D) BDNF is enhanced by upregulation in the cAMP cascade, as occurs with treatments for depression.

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