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Imagine You Are in Charge of Research and Development of a Pain

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Imagine you are in charge of research and development of a pain medication program at a major pharmaceutical company. Assuming that you are targeting the serotonergic system in your drug development program, what pain model should you focus on? What kinds of changes in pain sensitivity have been associated with this pain model? List two different serotonergic receptors for which agonist drugs have been successful in alleviating pain in animal research.

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The pain model to focus on is neuropathi...

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