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How Do Urea and Formamide Denature DsDNA

Question 5

Multiple Choice

How do urea and formamide denature dsDNA?


A) by intercalating between base pairs and disrupting van der Waals interactions
B) by forming ionic bonds with the backbone phosphates
C) by competing effectively with the H-bonding between the base pairs
D) by changing the pH to cause hydrolysis

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