Which of the Following Statements Explains Why Sulfonamides Are Effective

Multiple Choice

Which of the following statements explains why sulfonamides are effective antibiotics?

A) They serve as analogs of p-aminobenzoic acid and block bacterial synthesis of folate.
B) They act as inhibitors of bacterial dihydrofolate reductase,thus preventing production of tetrahydrofolate.
C) They act as suicide substrates for the enzyme dihydropteroate synthetase.
D) They do not affect humans because folate is a vitamin.