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What Is the Mechanism of Action of the Sipuleucel-T Prostate

Question 4

Multiple Choice

What is the mechanism of action of the sipuleucel-T prostate cancer vaccine?


A) Dendritic cells are incubated with a fusion protein containing prostate specific antigen (PSA) and GM-CSF.
B) A plasmid that codes for an antibody that expresses prostate specific antigen (PSA) , and dendritic cells present PSA to T cells.
C) A single B cell clone that is tumor specific is grown in the lab and infused into the patient to produce large amounts of tumor specific antibody.
D) Patient tumor cells are exposed to a viral vector containing a gene for prostate specific antigen (PSA) , and then the tumor cells are infused into the patient to stimulate an immune response.

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