The Relationship Between Malaria and the Allele That Produces Sickle-Cell

Multiple Choice

The relationship between malaria and the allele that produces sickle-cell anemia in humans is an example of balancing selection because

A) malaria causes selection against individuals carrying the sickle-cell allele to be 100%.
B) individuals that are heterozygous for the sickle-cell allele have a selective advantage against malaria over homozygous normal and homozygous sickle-cell individuals.
C) malaria produces mortality rates of about 50% in both normal hemoglobin individuals and sickle-cell individuals.
D) malaria kills 50% of children with the sickle-cell allele, and a similar proportion of adults with the allele.
E) mortality is roughly equal between people dying from malaria and people dying from sickle-cell anemia.