Which of the Following Statements About Enzyme-Catalyzed Isomerization of Glucose-6-Phosphate

Multiple Choice

Which of the following statements about enzyme-catalyzed isomerization of glucose-6-phosphate to fructose-6-phosphate is not true?

A) The mechanism is totally different from the laboratory version of the enediol rearrangement.
B) The first step is acid- and base-catalyzed ring opening.
C) The second step is a base-catalyzed enediol rearrangement.
D) The third step is acid- and base-catalyzed conversion of the enediol to a ketone.
E) The fourth step is acid- and base-catalyzed ring closure.