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Penicillin-Binding Proteins (Pbps) Are Proteins Located in the Periplasmic Space

Question 52

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Penicillin-binding proteins (pbps) are proteins located in the periplasmic space in Gram-negative bacteria and are involved in synthesizing the cell wall. Thus, they are a target for antibiotics and are of interest to drug developers. Describe how one could obtain these pbps for further study.

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After harvesting and washing cells, one ...

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