Using the Techniques of Genetic Engineering,you Design a Cytoplasmic Protein

Multiple Choice

Using the techniques of genetic engineering,you design a cytoplasmic protein you want to accumulate within the ER of yeast cells.To accomplish this goal,you need to

A) do nothing; all proteins go through the ER.
B) incorporate appropriate mannose-6-phosphate groups.
C) incorporate the appropriate DNA sequence(s) to create signal sequences into mature peptide.
D) incorporate radioactive amino acids into the protein.
E) incorporate the appropriate DNA sequence(s) to create signal sequences into the mature peptide.