Dihydrofolate Reductase and Thymidylate Synthetase Are Major Targets for Anticancer

Multiple Choice

Dihydrofolate reductase and thymidylate synthetase are major targets for anticancer drugs because

A) these enzymes are unique in cancer cells.
B) cancer cells lack sufficient amounts of these enzymes.
C) cancer cells grow rapidly and are very dependent upon the activities of these enzymes.
D) they donate one-carbon groups.
E) All of the above.