An Enzyme Works Well at as a Catalyst at a PH

Multiple Choice

An enzyme works well at as a catalyst at a pH of 7.2.It is found that catalytic activity is significantly less at a pH of 8.4.Which could likely cause the decrease in activity?

A) The protein has been degraded into its amino acids at pH 8.4.
B) The protein has changed shape due to a change in charge.
C) The protonation state of amino acids involved in the catalytic mechanism has changed.
D) B and C above.
E) All of the above.