Which Statement Is True About Catalytic Proficiencies

Multiple Choice

Which statement is true about catalytic proficiencies?

A) They are very useful for determining second-order rate constants.
B) From them you can calculate the amount of enzyme needed to achieve a specific rate of reaction.
C) They can easily be determined from the Lineweaver-Burk plot.
D) They are difficult to determine because the reactions without the enzyme are extremely slow.