The Following Are Important Steps in the Process of Endochondral

Multiple Choice

The following are important steps in the process of endochondral ossification. What is the correct order for these events?
1) Enlarged chondrocytes die.
2) Osteoblasts replace calcified cartilage with spongy bone.
3) Chondrocytes enlarge and the surrounding matrix begins to calcify.
4) Blood vessels grow around the edges of the cartilage.
5) Perichondrial cells become osteoblasts and produce a superficial layer of bone.

A) 3, 1, 5, 4, 2
B) 1, 3, 5, 4, 2
C) 1, 5, 3, 4, 2
D) 2, 3, 1, 5, 4
E) 3, 1, 4, 5, 2