Abnormal Chromosomes Are Frequent in Malignant Tumors

Multiple Choice

Abnormal chromosomes are frequent in malignant tumors. Errors such as translocations may place a gene in close proximity to different control regions. Which of the following might then occur to make the cancer worse?

A) An increase in non-disjunction
B) Expression of inappropriate gene products
C) A decrease in mitotic frequency
D) Death of the cancer cells in the tumor
E) Sensitivity of the immune system