Why Would Opioids Not Be a Good Choice or a First

Multiple Choice

Why would opioids not be a good choice or a first line of therapy for neuralgic pain?

A) Opioid receptors are not found on nerve endings.
B) Most neuralgic pain cannot be pinpointed,so trying to treat it with opioids increases the chance of dependence.
C) Opioids do not treat pain due to inflammation caused by neuralgic pain.
D) A higher dose is necessary to treat neuralgic pain,and opioids create an opportunity for tolerance and dependence.