Which of the Following Explains How Smoking Can Affect the Effectiveness

Multiple Choice

Which of the following explains how smoking can affect the effectiveness of theophylline?

A) Smoking decreases the half-life of theophylline by up to 50%,decreasing its effectiveness.
B) Smoking increases the effectiveness of theophylline and should be dosed accordingly for smokers.
C) Smoking increases the chances for adverse reactions to occur when taking theophylline.
D) Smoking further aggravates the condition theophylline is treating,preventing the drug from working.